Figure 9.
Blockade of Ih or INaP alone did not modify respiratory rhythm in the freely behaving adult rat. A, Bilateral microperfusion of riluzole (50 μm) into the preBötC of adult rat did not affect respiratory frequency. B, Diaphragm muscle activity was not modified by riluzole. C, Bilateral microperfusion of ZD7288 (100 μm) at the preBötCs did not change respiratory frequency. D, Diaphragm muscle amplitude was not changed by ZD7288. Values are shown as means ±SEM. *Indicates mean values significantly different from aCSF conditions with p < 0.05.