Figure 6.

Frequency of cigarette smoking was correlated with effects of nicotine replacement on behavioral performance and network topology. A, Effects of nicotine on no-go errors (no-go errors nicotine − no-go errors placebo) were significantly correlated with the number of cigarettes smoked per day. Higher-frequency smokers had greater reductions of no-go errors after nicotine replacement. B, Effects of nicotine on clustering (clustering nicotine − clustering placebo): higher-frequency smokers had greater nicotine-related reductions of network clustering.