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. 2013 Feb 6;33(6):2268–2280. doi: 10.1523/JNEUROSCI.4144-11.2013

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Copyright © 2013 the authors 0270-6474/13/332268-13$15.00/0

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Figure 7. — Effects of local gabazine (GABA_A receptor antagonist) injection in the vicinity of the recorded GPi neuron on responses evoked by local GPi microstimulation. A, Raw traces and PSTHs to local single-pulse stimulation (10 μA) (A1) and repetitive stimulation (10 μA, 100 Hz, 10 pulses) (A2) under control conditions. B, Raw traces and PSTHs after gabazine injection. Gabazine injection abolished inhibition to single-pulse stimulation (10 μA) (B1) and replaced inhibition to repetitive stimulation (10 μA, 100 Hz, 10 pulses) with excitation (B2). Stronger repetitive stimulation (60 μA, 100 Hz, 10 pulses) evoked inhibition, beginning at the latter half of the stimulation, and post-train excitation and inhibition (B3).