Table 2.

Distribution of 5-HT transporter gene-linked polymorphism in the healthy controls and in patients with Crohn’s disease

Genotype distribution	Healthy controls (HC) n=40 (%)	Crohn’s disease (CD) n=40 (%)
Wild-type (L/L)	16 (40%)	7 (17.5%)
Heterozygous (L/S)	16 (40%)	21 (52.5%)
Homozygous polymorphism (S/S) S-genotype (L/S + S/S)	8 (20%) 24 (60%)	12 (30%) 33 (82.3%)*
Allele (no. and %)
Allele (L)	48 (60%)	35 (43.8%)
Allele (S)	32 (40%)	45 (56.2%)

Healthy controls vs. patients with Crohn’s disease

*Fisher exact test, two-sided P=0.04