TABLE 2.
Study | Year | Age (Years) | No. of Patients | Conditioning | NRM | OS at 2 Years |
---|---|---|---|---|---|---|
Auner et al77 | 1991–1996 | 60–64 | 383 | Melphalan | 3.9 | 62.5 |
65–69 | 75 | 8.0 | 55.3 | |||
> 70 | 2 | NA | NA | |||
1996–2000 | 60–64 | 1,835 | 3.6 | 77.6 | ||
65–70 | 718 | 4.1 | 71.9 | |||
> 70 | 100 | 4.0 | 70.8 | |||
2001–2005 | 60–64 | 4,253 | 2.4 | 81.1 | ||
65–69 | 2,478 | 2.7 | 79.3 | |||
> 70 | 497 | 2.4 | 72.7 | |||
2006–2010 | 60–64 | 6,518 | 1.8 | 86.3 | ||
65–69 | 3,860 | 2.1 | 82.9 | |||
> 70 | 740 | 2.0 | 80.2 | |||
Sharma et al78 | 2008–2011 | 60–64 | 2,617 | Melphalan | 2.0 | 85 |
65–69 | 2,049 | 83 | ||||
> 70 | 946 |
Abbreviations: ASCT, autologous stem cell transplantation; NRM, non-relapse mortality; NA, not available; OS, overall survival.