Table 1.
Patient and treatment-related characteristics stratified by patients with xerostomia and no xerostomia for the studied follow-up times.
Note: the right-most column is a fusion of the two adjacent follow-up times.
| <6m | 6–11m | 12–24m | 6–24m | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Xerostomia | No Xerostomia |
Xerostomia | No Xerostomia |
Xerostomia | No Xerostomia |
Xerostomia | No Xerostomia |
|||||
| (n=15) | (n=40) | (n=5) | (n=30) | (n=5) | (n=29) | (n=10) | (n=43) | |||||
| Mean±SD | Mean±SD | p | Mean±SD | Mean±SD | p | Mean±SD | Mean±SD | p | Mean±SD | Mean±SD | p | |
| Age [y] | 56±7 | 57±10 | 0.89 | 51±9 | 58±9 | 0.20 | 54±10 | 57±12 | 0.69 | 53±9 | 58±10 | 0.20 |
| Dmeancontra [Gy] | 24.9±12.1 | 15.3±8.2 | 0.002* | 26.4±2.7 | 19.5±10.7 | 0.01* | 22.8±6.0 | 15.5±9.4 | 0.08 | 24.6±4.8 | 17.4±10.7 | 0.003* |
| Dmeanipsi [Gy] | 43.8±20.3 | 25.1±12.6 | <0.0001* | 38.6±14.9 | 29.2±17.1 | 0.06 | 41.0±14.3 | 27.6±15.6 | 0.10 | 39.8±13.8 | 29.4±17.3 | 0.02* |
| WMSFM Pre-RT | 3.5±1.5 | 2.4±0.8 | 0.01* | 3.0±1.2 | 2.7±1.3 | 0.40 | 3.8±1.7 | 2.5±1.1 | 0.06 | 3.4±1.4 | 2.6±1.2 | 0.06 |
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | |||||
|
Chemotherapy N/A |
14 (93) | 25 (63) | 0.02* | 5 (100) | 19 (63) | 0.24 | 4 (80) | 14 (48) | 0.60 | 9 (90) | 26 (60) | 0.22 |
| 1 (7) | 4 (10) | - | 5 (17) | - | 2 (7) | - | 6 (14) | |||||
| 1 (7) | 4 (10) | - | 5 (17) | - | 2 (7) | - | 6 (14) | |||||
| T-stage | 0.17 | 0.77 | 0.18 | 0.63 | ||||||||
| 1 | 4 (27) | 15 (38) | 1 (20) | 12 (40) | 1 (20) | 11 (38) | 2 (20) | 18 (42) | ||||
| 2 | 4 (27) | 13 (33) | 2 (40) | 7 (23) | 3 (60) | 7 (24) | 5 (50) | 12 (28) | ||||
| 3 | 1 (7) | 4 (10) | - | 5 (17) | 1 (20) | 1 (3) | 1 (10) | 4 (9) | ||||
| 4 | 2 (13) | 7 (18) | 1 (20) | 5 (17) | - | 2 (7) | 1 (10) | 6 (14) | ||||
| N/A | 4 (27) | 1 (3) | 1 (20) | 1 (3) | - | 3 (10) | 1 (10) | 3 (7) | ||||
| Tumor site | 0.03* | 0.60 | 0.79 | 0.19 | ||||||||
| Base of tongue | 2 (13) | 7 (18) | 1 (20) | 6 (20) | 1 (20) | 8 (28) | 2 (20) | 8 (19) | ||||
| Buccal mucosa | - | 2 (5) | - | 1 (3) | 1 (20) | - | 1 (10) | 1 (2) | ||||
| Floor of mouth | - | 1 (3) | - | 1 (3) | - | - | - | 1 (2) | ||||
| Larynx | - | 6 (15) | 1 (20) | 4 (13) | - | - | 1 (10) | 5 (11) | ||||
| Max sinus | - | 1 (3) | - | 1 (3) | - | - | - | 1 (2) | ||||
| Nasal cavity | - | 1 (3) | - | - | - | 1 (3) | - | 1 (2) | ||||
| Nasopharynx | 3 (20) | 5 (13) | 2 (40) | 4 (13) | 2 (40) | 3 (10) | 4 (40) | 5 (12) | ||||
| Oral tongue | 2 (13) | 5 (13) | 1 (20) | 4 (13) | 1 (20) | 2 (7) | 2 (20) | 5 (12) | ||||
| Parotid | 1 (7) | 1 (3) | - | - | - | 3 (10) | - | 3 (7) | ||||
| Submandibular gland | - | 1 (3) | - | - | - | - | - | 1 (2) | ||||
| Retromolar trigone | - | 1 (3) | - | - | - | 1 (3) | - | - | ||||
| Thyroid | - | 1 (3) | - | - | - | - | - | - | ||||
| Tonsil | 4 (27) | 8 (20) | - | 8 (27) | - | 2 (7) | - | 10 (43) | ||||
| Unknown primary | 3 (20) | - | - | 1 (3) | - | 1 (3) | - | 2 (5) | ||||