Table 2.
Experimental setting | MMTV-cre Mammary gland |
MMTV-PyVT Mammary gland tumor |
MMTV-Tg(LINK-A) Mammary gland tumor |
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---|---|---|---|---|---|---|
IgG | α-PKA | IgG | α-PKA | IgG | α-PKA | |
PKA Complex | KAP3 | KAP3 | KAP3 | |||
p-PKA-C-α (Thr197) | p- PKA-C-α (Thr197) | PKA-C-α | ||||
p- PKA-C-β (Thr197) | p- PKA-C-β (Thr197) | KAP2 | ||||
KAP2 | KAP2 | KAP0 | ||||
KAP0 | KAP0 | PKA-C-β | ||||
KAP1 | KAP1 | KAP1 | ||||
Ubiquitin Machinery | p-TRIM71 (Ser3) | p-TRIM71 (Ser3) | TRIM71 | |||
Ubiquitin | ||||||
UBA1 | ||||||
UB2D3 | ||||||
Ubiquitin Substrates | Rb | Rb | Ub-Rb (Lys803) | |||
P53 | P53 | Ub-p53 (Lys126) |