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. 2013 Feb 20;33(8):3390–3401. doi: 10.1523/JNEUROSCI.3346-12.2013

Figure 2.

Figure 2.

Identification of the recruited cortical neuronal network by LC stimulation. A–C, Photomicrographs of immunostained sections for c-Fos in the frontoparietal cortex induced by LC stimulation in controls or DSP-4 treated rats. D–H, Photomicrographs of double-immunostained sections for c-Fos (SG, blue–gray nuclei) and different neuronal markers (DAB, brown): COX-2 pyramidal cells (D) and GABA interneurons expressing PV (E), SOM (F), NOS (G), or VIP (H). Filled arrows show activated cells, whereas open arrows indicate absence of c-Fos expression. I, Quantitative analysis of double-labeled c-Fos COX-2 pyramidal cells or GABA interneuron subtypes in layers II–IV of the ipsilateral frontoparietal cortex. *p < 0.05, **p < 0.01, one-way ANOVA and a Newman–Keuls post hoc test. Scale bars: A–C, 100 μm; insets, 20 μm; D–G, 20 μm; insets, 10 μm.