Figure 1.

MPP3 localization in the developing cortex. A, B, In E12.5 dorsal telencephalon, MPP3 is enriched at the apical membrane at the ventricular zone. C–E, Expression of MPP3 at the apical membrane is highest at E12.5 (C), decreased at E14.5 (D), and clearly diminished at E18.5 (E). Arrows in A and C–E indicate apical membrane. F–H, Partial colocalization (H) of MPP3 (F) with the apical protein PALS1 (G). I–K, Partial colocalization (K) of MPP3 (I) with adherens junction protein Nectin1 (J). Scale bars, 20 μm.