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. 2019 Jul 10;14(7):e0218491. doi: 10.1371/journal.pone.0218491

Table 1. Characteristics of the 3 newborns with congenital Chagas infection.

Newborn 1 Newborn 2 Newborn 3
Maternal country Bolivia Bolivia Bolivia
Maternal age (years) 25 26 38
Maternal disease status Chronic Chronic Chronic
Pregnancy Singleton Singleton Singleton
Gestational age (weeks) 38+2 38+3 36+6
Mode of delivery Vaginal—instrument assisted Vaginal—spontaneous Elective caesarian
Gender Female Male Male
Clinical manifestations at birth No No Yes
PCR at birth Positive Positive Positive
PCR at 1 month of life Positive Positive Positive
Treatment Benznidazole Benznidazole Benznidazole
Treatment dose (mg/Kg/day) 5 10 10
Treatment age of onset (days) 45 30 15
Length of treatment (days) 49 60 60
Secondary effects Moderate neutropenia - -
1st Serology (Age months /result) 9 / Positive 9 / Positive 3 / Positive
2nd Serology (Age months /result) 12.9 / Negative 15.6 / Negative 3.8 / Positive
3rd Serology (Age months /result) - - 20.2 / Negative
PCR post-treatment (Age months /result) 12.9 / Negative 9.9/ Negative 3 / Negative
Total blood samples obtained 4 5 6