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C-peptide concentration (A) and AUC (B) and glucagon concentration (C) and AUC (D) responses to either a high-protein or a high-carbohydrate breakfast and a standardized lunch in individuals with T2D. Arrows indicate when meals were consumed. Values are means ± SEMs, n = 12. *Between breakfast and lunch, P < 0.05; **Different from corresponding lunch, P < 0.05; †Different by meal composition, P < 0.05. CHO, carbohydrate breakfast; PRO, protein breakfast; T2D, type 2 diabetes.
