MAO-A enzymatic activities in Rines KO and WT mice. The enzymatic activities were measured in the LC, raphe nuclei (RN), substantia nigra (SN), prefrontal cortex (PFC), and basolateral nucleus of the amygdala (BLA) in WT and Rines KO mouse brains. Increased MAO-A activity was observed in the LC region of Rines KO mice. WT and KO, n = 7–14; *p < 0.05, Student's t test. WT values are indicated as 100%.