Table 2.

Amounts of monoamines and their metabolites

Values are presented as mean ± SEM (pg/mg protein). n = 7–9 mice per condition; *p < 0.05, Student's t test compared with WT mice. There were significant genotype effects for 5-HT and NE contents in LC and for NE contents in amygdala analyzed by two-way ANOVA (^#p_genotype < 0.05, ^##p_genotype < 0.01). There were significant effects of the interaction of genotype by treatment for 5-HT and NE contents in the prefrontal cortex and HVA contents in the amygdala analyzed by two-way ANOVA (^§p_{genotype × treatment} < 0.05, ^§§p_{genotype× treatment} < 0.01). DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; MHPG, 3-methoxy-4-hydroxyphenylethyleneglycol; 5-HIAA, 5-hydroxyindoleacetic acid; ND, not detected.