Table 1. Exon-intron junctions containing predicted wild type structures.

Junction	Nucleotides	ΔG37° (kcal/mol)	Average base pair conservation (%)	Number of speciesa
E1-I1	137–150 of E1 and E1+1 to E1+7 of I1	−9.5	94.3	5
I1-E2	E2−29 to E2−1 of I1 and 1–3 of E2	−9.0	97.4	6
E2-I2	82–87 of E2 and E2+1 to E2+27 of I2	−11.6	99.2	6
E2-I2	68–87 of E2 and E2+1 to E2+46 of I2	−19.2	99.0	6
E3-I3	18–87 of E3	−25.9	92.9	18
I3-E4	E4−43 to E4−1 of I3 and 1–15 of E4	−14.0	100.0	2
I3-E4	E4−25 to E4−1 of I3 and 1–6 of E4	−6.4	100.0	1
I4-E4A	E4A−38 to E4A−1 of I4 and 1–31 of E4A	−24.1	97.5	3
I4A-E5	E5−63 to E5−1 of I4A and 1–5 of E5	−15.4	100.0	5
E5-I5	4–56 of E5 and E5+1 to E5+15 of I5	−13.5	100.0	2
E5-I5	50–56 of E5 and E5+1 to E5+53 of I5	−16.5	100.0	2
E6-I6	133–198 of E6 and E6+1 of I6	−18.2	98.8	8
E6-I6	164–198 of E6 and E6+1 to E6+29 of I6	−11.7	100.0	1
I6-E7	E7−35 to E7−1 of I6 and 1–28 of E7	−14.5	99.0	4
I6-E7	E7−1 of I6 and 1–48 of E7	−17.0	96.3	9
E7-I7	E7+1 to E7+21 of I7	−2.7	100.0	2
I7-E8	E8−19 to E8−1 of I7 and 1–27 of E8	−13.0	100.0	1
I7-E8	E8−26 to E8−1 of I7 and 1–40 of E8	−17.9	98.7	4
I8-E9	E9−41 to E9−1 of I8 and 1–21 of E9	−11.0	100.0	4
I8-E9	E9−15 to E9−1 of I8 and 1–5 of E9	−0.4	100.0	1
I9-E10	E10−14 to E10−1 of I9 and 1–7 of E10	−4.5	94.1	7
E10-I10	73–93 of E10 and E10+1 to E10+31 of I10	−19.3	93.3	4
I10-E11	E11−3 to E11−1 of I10 and 1–30 of E11	−6.4	94.4	5
I10-E11	E11−10 to E11−1 of I10 and 1–40 of E11	−10.9	90.0	4
E11-I11	78–82 of E11 and E11+1 to E11+60 of I11	−17.7	92.1	5
I11-E12	E12−61 to E12−1 of I11 and 1–8 of E12	−20.1	94.6	6
I11-E12	E12−11 to E12−1 of I11 and 1–51 of E12	−16.0	95.4	5
E12-I12	77–113 of E12 and E12+1 to E12+22 of I12	−17.9	96.1	5
E12-I12	100–113 of E12 and E12+1 to E12+53 of I12	−11.9	94.9	5
I12-E13	E13−9 to E13−1 of I12 and 1–32 of E13	−6.8	94.0	7

^a Non-human primates.