Table 1.
Patients and tumor characteristics
| Number of patients | 19503 |
| Mean age (±SD) | 51.8 (±12.6) |
| <40 years old | 3101 (16.6%) |
| ≥40 years old | 15604 (83.4%) |
| Histopathologic subtype | |
| Invasive ductal cancer | 7726 (76.9%) |
| Invasive lobular cancer | 649 (6.5%) |
| Invasive mixed type | 425 (4.2%) |
| Other | 1241 (12.4%) |
| Histologic grade | |
| I | 562 (7.7%) |
| II | 3416 (46.8%) |
| III | 3320 (45.5%) |
| Receptor status | |
| ER | 5745 (72.5%) |
| PR | 4736 (62.5%) |
| HER-2 | 1659 (21.8%) |
| Ki-67 (≤%14) | 378 (%35.0) |
| Pathologic stages at the time of diagnosis | |
| Stage I+II | 4990 (76.8%) |
| Stage III+IV | 1728 (23.2%) |
| Obstetric history | |
| Nulliparous | 1281 (13.6%) |
| Monoparous | 1227 (13.1%) |
| Spontaneous abortion | 1494 (19.3%) |
| Induced abortion | 2326 (30.0%) |
| Molecular subtypes | |
| Luminal A | 3326 (57.7 %) |
| Luminal B | 1187 (50.3 %) |
| HER-2 | 555 (12.2 %) |
| TNG | 695 (8.1 %) |
| 5-year overall survival | 3555 (85.8%) |
| 10-year overall survival | 4826 (75.7%) |
ER: Estrogen; PR: Progesterone; TNG: triple negative