Table 2. Metabolites significantly modulated in HIGA mice in all of the 12, 22, and 32 week old.
| A. Metabolites significantly higher in HIGA mice in all of the 12, 22, and 32 week old. | ||||||
| 12 week old | 22 week old | 32 week old | ||||
| Metabolites | HIGA/Balb/c | p-value | HIGA/Balb/c | p-value | HIGA/Balb/c | p-value |
| Glucuronic acid-5TMS(2) | 2.89541 | <0.00001 | 2.49209 | <0.00001 | 2.06108 | <0.00001 |
| Inositol phosphate-7TMS | 1.53509 | 0.00010 | 1.75006 | 0.00099 | 1.85005 | 0.00009 |
| Myristic acid-TMS | 1.82336 | 0.00015 | 1.66276 | 0.00010 | 1.53618 | 0.00022 |
| Xylitol-5TMS | 1.45141 | 0.00017 | 1.45456 | 0.00008 | 1.82945 | 0.00010 |
| Indol-3-acetic acid-TMS | 1.25844 | 0.00215 | 1.21621 | 0.00509 | 1.18954 | 0.03450 |
| Inosine-4TMS | 20.18891 | 0.00415 | 18.56310 | 0.00001 | 2.17511 | 0.00683 |
| Galactitol-6TMS | 1.83617 | 0.00274 | 2.07812 | 0.00011 | 1.44513 | 0.03552 |
| Coniferyl alcohol-2TMS | 1.34618 | 0.00320 | 1.23151 | 0.02318 | 1.19172 | 0.03570 |
| Galactosamine-5TMS(1) | 1.66865 | 0.00442 | 1.24245 | 0.00229 | 1.46790 | 0.00190 |
| Glucosamine-5TMS(1) | 1.21603 | 0.00979 | 1.50628 | 0.00246 | 1.25321 | 0.02218 |
| Tyramine-3TMS | 1.20258 | 0.01817 | 1.28135 | 0.00231 | 1.24799 | 0.03695 |
| 5-Dehydroquinic acid-5TMS | 1.28379 | 0.02403 | 1.28189 | 0.02267 | 1.44342 | 0.00295 |
| 1,5-Anhydro-glucitol-4TMS | 1.23604 | 0.03318 | 1.25176 | 0.01222 | 1.23455 | 0.01073 |
| Galactose-5TMS(2) | 1.21511 | 0.03987 | 1.26687 | 0.00203 | 1.25862 | 0.00074 |
| Mannose-5TMS(2) | 1.21511 | 0.03987 | 1.26687 | 0.00203 | 1.25862 | 0.00074 |
| Allose-5TMS | 1.21511 | 0.03987 | 1.26687 | 0.00203 | 1.25862 | 0.00074 |
| B. Metabolites significantly lower in HIGA mice in all of the 12, 22, and 32 week old. | ||||||
| Metabolites | HIGA/Balb/c | p-value | HIGA/Balb/c | p-value | HIGA/Balb/c | p-value |
| Tyrosine-3TMS | 0.49751 | <0.00001 | 0.54995 | 0.02270 | 0.81751 | 0.03122 |
| Hypotaurine-3TMS | 0.74505 | 0.03020 | 0.79055 | 0.04874 | 0.35015 | 0.00033 |