Skip to main content
. 2019 Jul 10;14(7):e0219576. doi: 10.1371/journal.pone.0219576

Table 1. Characterization of inbred strains for naturally occurring hematopoietic neoplasms.

Disease Incidence, Latency, Typea Strain Emvs X/P-ERVs Involved in P-MLV Generationd Fv1
Locusb Expressionc Pmvs Xmvs
High, Early, T Cell AKR Emv11-14 SpH 13 20 10 Bxv1 n
C58 4–6 Emvs SpH 1 11 13 20 10 Bxv1 n
HRS Emv1,3 SpH 1 11 13 15 20 Bxv1 n
P Emv3 NT 1 20 10 13 n
PL 3–4 Emvs NT 1 13 20 n
SAMP7 Emv11+1Emv SpH 1 13 Bxv1 n
SAMP8 Emv11+7Emvs SpH 1 13 Bxv1 n
SAMP9 Emv11+2Emvs SpH 1 13 20 n
Moderate, Late, Low, T Cell or Non-T Cell C3H Emv1 Ind 1 13 15 20 IV1 n
C57BR Emv2 NT 1 11 13 20 10 Bxv1 IV1 n
CBA/J Emv1 Ag+ 1 13 15 20 13 IV1 n
MA/My Emv8,9 (Ind),Ag+ 1 20 Bxv1 n
NOD Emv30 SpL 1 13 20 n
SAMP1 Emv11+2Emvs SpH 1 13 n
SAMP10 Emv11+5Emvs SpH 1 13 10 n
SAMR5 3Emvs - 1 13 20 n
SEA Emv1,3 SpL,Ind 1 11 13 20 n
SJL Emv9,10 SpL,Ind,Ag+ 1 13 n
NON Emv30 SpL 1 13 20 n
SAMP6 2Emvs - 1 13 10 n
SAMP11 Emv11 SpH 1 13 20 n
SAMR1 2Emvs SpL 1 13 20 n
SAMR4 2Emvs SpL 1 13 20 n
F/St Emv+ SpH 13 10 Bxv1 nr
LP Emv5 NT 1 11 13 nr
KK Emv+ NT 1 15 20 nr
NZW Emv+ NT 1 11 13 20 nr
RF Emv1,2 Ag+ 1 13 20 10 nr
SM Emv1 NT 1 11 13 20 nr
DBA/2 Emv3 SpL 1 13 20 10 Bxv1 d
NZO Emv+ NT 1 11 13 20 d
A Emv1 Ind,Ag+ 1 13 20 10 IV1 b
BALB/c Emv1 Ind,Ag+ 1 11 13 20 Bxv1 b
C57BL Emv2 (Ind) 1 11 13 15 20 10 Bxv1 IV1 b
I Emv1,3 Ag- 1 11 13 20 10 13 Bxv1 IV1 b
YBR Emv+ NT 1 11 13 20 10 b

aDisease type and incidence was compiled from [23, 44, 5765].

bMany Emvs have assigned numbers [6, 46]; Emv+, strains carrying uncharacterized PCR-detected Emv env sequences.

cExpression is identified as: SpH, spontaneous high; SpL, spontaneous low; Ag+, viral antigen positive; Ind, inducible by iododeoxyuridine; -, no expression; NT, not tested.

dThe X/P-MLV ERVs that contribute to P-MLVs were previously identified [13].