Table 1.
Occupational risk factor | No. of studies | No. of cases | MetaRR | 95% CI | Q | P-value | I2 (%) |
---|---|---|---|---|---|---|---|
Pesticides | 18 | 3,474 | 1.15 | 1.01–1.32 | 110 | <0.001 | 84 |
Coh | 13 | 3,067 | 1.13 | 0.97–1.32 | 96 | <0.001 | 86 |
CC | 5 | 407 | 1.26 | 0.86–1.83 | 15 | 0.006 | 33 |
Organochlorines | 17 | 2,730 | 1.08 | 1.03–1.14 | 43 | 0.49 | 0 |
Coh | 10 | 1,003 | 1.12 | 1.05–1.19 | 13 | 0.6 | 0 |
CC | 7 | 1,727 | 0.99 | 0.89–1.10 | 26 | 0.53 | 0 |
Chromium | 8 | 964 | 1.19 | 1.07–1.34 | 10 | 0.18 | 31 |
Shiftwork | 6 | 1,355 | 1.25 | 1.05–1.49 | 36 | <0.000 | 78 |
Coh | 4 | 861 | 1.14 | 0.98–1.32 | 11 | 0.052 | 55 |
CC | 2 | 494 | 1.50 | 0.91–2.48 | 21 | <0.000 | 90 |
Flight personnel | 3 | 180 | 1.26 | 0.90–1.76 | 8.9 | 0.031 | 66 |
Pilots | 3 | 163 | 1.41 | 1.02–1.94 | 5.4 | 0.07 | 63 |
Occupational physical activity | 18 | 3,417 | 0.90 | 0.80–1.02 | 55 | <0.000 | 69 |
Coh | 10 | 1,684 | 0.87 | 0.80–0.94 | 8.5 | 0.48 | 0 |
CC | 8 | 1,733 | 0.91 | 0.68–1.20 | 44 | <0.000 | 84 |
Whole body vibration | 10 | 6,224 | 1.03 | 0.98–1.09 | 66 | <0.000 | 77 |
Coh | 5 | 4,768 | 1.01 | 0.98–1.05 | 19 | 0.004 | 69 |
CC | 5 | 1,456 | 1.31 | 1.00–1.72 | 47 | <0.000 | 83 |
Farming, farmers | 26 | 66,749 | 0.99 | 0.95–1.02 | 118 | <0.001 | 79 |
Coh | 15 | 65,448 | 0.97 | 0.94–1.00 | 90 | <0.001 | 58 |
CC | 11 | 1,301 | 1.04 | 0.90–1.21 | 21 | 0.021 | 33 |
Organophosphates | 7 | 1,350 | 0.98 | 0.87–1.11 | 8 | 0.44 | 0 |
Coh | 4 | 901 | 0.97 | 0.82–1.14 | 1.1 | 0.77 | 0 |
CC | 3 | 449 | 0.99 | 0.78–1.25 | 7 | 0.15 | 41 |
Carbamates | 5 | 520 | 1.05 | 0.89–1.24 | 8 | 0.22 | 27 |
Triazines | 4 | 471 | 1.02 | 0.92–1.14 | 7 | 0.13 | 45 |
Cadmium | 7 | 71 | 1.12 | 0.82–1.53 | 6 | 0.42 | 0 |
Cutting fluids | 8 | 446 | 1.03 | 0.92–1.16 | 9 | 0.42 | 0 |
Coh | 5 | 285 | 1.03 | 0.88–1.21 | 7 | 0.29 | 18 |
CC | 3 | 161 | 0.89 | 0.66–1.21 | 0.9 | 0.64 | 9 |
Acrylonitrile | 4 | 54 | 0.93 | 0.71–1.21 | 0.41 | 0.94 | 0 |
Rubber manufacturing | 15 | 923 | 0.98 | 0.87–1.09 | 0.33 | 0.005 | 55 |
Ionizing radiation | 9 | 1,624 | 1.07 | 0.97–1.17 | 20 | 0.009 | 61 |
MetaRR, meta relative risk; CI, confidence interval; Coh, cohort study; CC, case control study.