Figure 1.

The grouping of subjects and data are shown in Figure 1. The subjects consisted of a group diagnosed with anti-AQP4 antibody positive optic neuritis shortly after onset of optic neuritis and received maintenance therapy continuous from acute treatment for onset attack of optic neuritis (group A), and a group diagnosed with optic neuritis before anti-AQP4 antibody was discovered and subsequently received maintenance therapy upon detection of anti-AQP4 antibody after a time lapse from acute treatment of onset attack (group B). For patients in group B, the data from onset attack to before start of maintenance therapy [group B (pre)] and the data after initiation of maintenance therapy [group B (post)] were analyzed separately.