Table 1.

Demographic, clinical and outcome data of all patients with aquaporin-4 antibody-positive optic neuritis analyzed.

No. of patients (eyes)	69 patients (103 eyes)
Female/male	62/7 (89.9% female)
Mean age at onset (range: median) years	49.9 (8–72: median 51.5)
Mean disease duration (range) months	100.0 ± 74.0 (3.0–400)
Onset attack:
Optic neuritis	65/69 patients (94.2%)
Transverse myelitis	4/69 patients (5.8%)
Course of disease:
Optic neuritis only	51/69 patients (73.9%)
Bilateral episodes	34/69 patients (49.3%)
Simultaneous bilateral episodes	12/69 patients (17.4%)
Visual outcome:
≥1.0	23/103 eyes (22.3%)
≤0.1	58/103 eyes (56.3%)
Total blindness	14/103 eyes (13.6%)
Bilateral visual acuity ≤0.1	14/69 patients (20.3%)
Unilateral visual acuity ≤0.1	25/69 patients (36.2%)
Acute treatment
High-dose intravenous methylprednisolone	55/69 patients(79.7%)
High-dose intravenous methylprednisolone + plasma exchange	14/69 patients (20.3%)