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. 2019 Jul 10;14(7):e0215557. doi: 10.1371/journal.pone.0215557

Fig 3. Aggregation of immune cell infiltrate in mouse liver injury.

Fig 3

Inflammatory infiltrates in liver tissue of control, 4, 8 and 20-week TAA-treated C57Bl/6 mice and control, 1 day and 4 weeks CCl4 treated C57Bl/6 and BALB/c mice. Representative images of CD45 stained liver sections from (A) non-injured control; (B) 20-week TAA and (C) 4 week CCl4 treated mice. Scale represents 100μM. (D) Total CD45+ cells were quantified per field of view with 4–10 fields counted per section. Bars represent mean+SEM. (E) Immune cell aggregates were quantified (≥5 CD45+ cells per cluster) per field of view (FOV). Bars represent mean+SEM. Mann-Whitney test was performed to assess significance from control where * p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 (n = 5–8 per group).