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. 2019 Jul 11;75(1):90–101.e5. doi: 10.1016/j.molcel.2019.04.020

Figure 2.

Figure 2

Structure of Cas18-Cas24-Csn28 Monomer

(A) Perpendicular views of the 3.2-Å-resolution cryo-EM map of the monomer complex. Density for the Cas2 dimers is shown but was not of sufficient quality for the subunits to be positioned uniquely.

(B) Cartoon of the final model colored as in (A). For Cas2, only the C-terminal Cas1-interacting region is shown.

(C) The 4-fold repeat unit of Cas12-Cas21-Csn22 is colored to highlight distinct conformations of the components.