Figure 7.

Lung pathology in immunized mice after RSV challenge. (A) Representative photomicrographs of lung tissue sections stained with H&E, H&CR, and PAS. Scale bars indicate 100 μm. The arrows indicate representative spot area displaying severe H&E and PAS staining. The inserted boxes indicate the enlarged photos on H&CR stained eosinophilic cells The arrows mark representative inflamed area. (B) The histopathology was scored for inflammation blindly using a 1–5 scoring system. (C) The eosinophil infiltration in H&CR stained sections of individual lung tissue of the immunized mice. The infiltrated eosinophils per field were quantified in the lung airways. (D) The percentage of PAS stained lung section area with PAS positive expression from individual mouse.