Table 1.
Parameter | Value | Evaluable No. patients |
CR No. patients (%) |
PR No. patients (%) |
SD No. patients (%) |
PD No. patients (%) |
---|---|---|---|---|---|---|
Number of patients | 31 | 28 | 17 (60.7%) | 8 (28.5%) | 1 (3.5%) | 2 (7.1%) |
Age, median y (range) | 49 (17-77) | |||||
Gender (M / F) | 15M / 16F | |||||
Ann Arbor stage no. patients (%) | ||||||
Stage I-II | 3 (9.6%) | |||||
Stage III-IV | 28 (90.3%) | |||||
IPI score no. patients (%) | ||||||
Low + Low-intermediate (0-2) | 11 (35.4%) | |||||
High-intermediate +High (3-5) | 20 (64.5%) | |||||
Histologic subtype no. patients(%) | ||||||
PTCL-NOS | 11 (35.4%) | 10 | 7 (70%) | 3 (30%) | ||
ATL | 10 (32.2%) | 8 | 5 (62.5%) | 2 (25%) | 1 (12.5%) | |
AITL | 4 (12.9%) | 4 | 3 (75%) | 1 (25%) | ||
CGDTCL | 2 (6.4%) | 2 | 1 (50%) | 1 (50%) | ||
Hepatosplenic TCL | 2 (6.4%) | 2 | 1 (50%) | 1 (50%) | ||
Other* | 2 (6.4%) | 2 | 2 (100%) |
Abbreviations: PTCL-NOS, peripheral T cell lymphoma not-otherwise-specified; ATL, adult T cell leukemia/lymphoma; AITL, angioimmunoblastic lymphoma; CGDTCL, cutaneous gamma delta T cell lymphoma
Other histologic subtypes included one case of ALK-negative anaplastic large cell lymphoma and NK/T cell lymphoma