Figure 3.

Interleukin‐6 (IL‐6) level in serum and monocytes from patients with chronic obstructive pulmonary disease‐associated pulmonary hypertension (COPD‐PH) and controls. (a) The expression of RORC2 in control CD4⁺ T cells upon CD3/CD28 activation and various levels of exogenous IL‐6. (b) The expression of RORC2 in patient CD4⁺ T cells upon CD3/CD28 activation and various levels of exogenous IL‐6. Repeated measures one‐way analysis of variance followed by Dunnett's multiple comparison tests. (c) The serum IL‐6 level in COPD‐PH patients and healthy controls. (d) IL‐6 mRNA expression in ex vivo monocytes. (e) IL‐6 mRNA expression in lipopolysaccharide‐stimulated monocytes. Unpaired t‐test with Welch's correction.