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. 2019 Feb 21;34(8):1266–1279. doi: 10.1007/s00380-019-01363-8

Table 5.

Logistic regression analysis of TCFA

Analysis
Single Multiple
OR (95% CI) p-value OR (95% CI) p-value
Age (years) 2.21 (0.83–5.89) 0.113
Male 1.35 (0.45–4.02) 0.593
Body mass index 0.51 (0.20–1.34) 0.174
Diabetes mellitus 0.43 (0.14–1.29) 0.133
Hypertension 1.37 (0.50–3.78) 0.544
Dyslipidemia 0.62 (0.19–2.09) 0.444
Chronic kidney disease 1.87 (0.61–5.77) 0.276
Current smoker 1.07 (0.39–2.96) 0.894
Obstructive sleep apnea 3.77 (1.28–11.1) 0.016
Apnea hypopnea index 11.7 (2.37–57.6) 0.003 7.55 (1.35–42.4) 0.022
Family history of coronary artery disease 0.49 (0.12–2.08) 0.333
History of PCI or CABG 0.39 (0.14–1.05) 0.063
History of myocardial infarction 0.48 (0.16–1.46) 0.196
Prior statin use 0.20 (0.06–0.64) 0.006 0.46 (0.12–1.68) 0.238
Prior aspirin use 0.87 (0.34–2.23) 0.767
Prior clopidogrel use 0.66 (0.22–1.94) 0.446
Prior ACEI or ARB 0.78 (0.27–2.24) 0.648
Prior calcium channel blocker use 0.92 (0.33–2.58) 0.875
Prior beta blocker use 0.82 (0.29–2.27) 0.700
Prior eicosapentaenoic acid 0.47 (0.09–2.60) 0.386
Prior ezetimibe 0.29 (0.03–2.75) 0.282
Hemoglobin (g/dl) 0.39 (0.10–1.49) 0.169
HbA1c (%) 0.39 (0.14–1.05) 0.063
Glucose (mg/dl) 0.40 (0.13–1.19) 0.100
LDL-C (mg/dl) 3.02 (1.09–8.40) 0.033
Triglyceride (mg/dl) 0.38 (0.14–1.01) 0.053
HDL-C (mg/dl) 0.38 (0.14–1.01) 0.053
LDL-C to HDL-C ratio 7.11 (2.09–24.2) 0.002 4.53 (1.15–17.8) 0.030
Acute coronary syndrome 1.41 (0.53–3.71) 0.492
ST-elevation myocardial infarction 3.13 (1.12–8.71) 0.029 1.97 (0.57–6.77) 0.284
Non ST-elevation myocardial infarction 0.39 (0.12–1.23) 0.108

OR odds ratio, CI confidence interval, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, TIA transient ischemic attack, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker