Table 5.
Logistic regression analysis of TCFA
Analysis | ||||
---|---|---|---|---|
Single | Multiple | |||
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age (years) | 2.21 (0.83–5.89) | 0.113 | ||
Male | 1.35 (0.45–4.02) | 0.593 | ||
Body mass index | 0.51 (0.20–1.34) | 0.174 | ||
Diabetes mellitus | 0.43 (0.14–1.29) | 0.133 | ||
Hypertension | 1.37 (0.50–3.78) | 0.544 | ||
Dyslipidemia | 0.62 (0.19–2.09) | 0.444 | ||
Chronic kidney disease | 1.87 (0.61–5.77) | 0.276 | ||
Current smoker | 1.07 (0.39–2.96) | 0.894 | ||
Obstructive sleep apnea | 3.77 (1.28–11.1) | 0.016 | ||
Apnea hypopnea index | 11.7 (2.37–57.6) | 0.003 | 7.55 (1.35–42.4) | 0.022 |
Family history of coronary artery disease | 0.49 (0.12–2.08) | 0.333 | ||
History of PCI or CABG | 0.39 (0.14–1.05) | 0.063 | ||
History of myocardial infarction | 0.48 (0.16–1.46) | 0.196 | ||
Prior statin use | 0.20 (0.06–0.64) | 0.006 | 0.46 (0.12–1.68) | 0.238 |
Prior aspirin use | 0.87 (0.34–2.23) | 0.767 | ||
Prior clopidogrel use | 0.66 (0.22–1.94) | 0.446 | ||
Prior ACEI or ARB | 0.78 (0.27–2.24) | 0.648 | ||
Prior calcium channel blocker use | 0.92 (0.33–2.58) | 0.875 | ||
Prior beta blocker use | 0.82 (0.29–2.27) | 0.700 | ||
Prior eicosapentaenoic acid | 0.47 (0.09–2.60) | 0.386 | ||
Prior ezetimibe | 0.29 (0.03–2.75) | 0.282 | ||
Hemoglobin (g/dl) | 0.39 (0.10–1.49) | 0.169 | ||
HbA1c (%) | 0.39 (0.14–1.05) | 0.063 | ||
Glucose (mg/dl) | 0.40 (0.13–1.19) | 0.100 | ||
LDL-C (mg/dl) | 3.02 (1.09–8.40) | 0.033 | ||
Triglyceride (mg/dl) | 0.38 (0.14–1.01) | 0.053 | ||
HDL-C (mg/dl) | 0.38 (0.14–1.01) | 0.053 | ||
LDL-C to HDL-C ratio | 7.11 (2.09–24.2) | 0.002 | 4.53 (1.15–17.8) | 0.030 |
Acute coronary syndrome | 1.41 (0.53–3.71) | 0.492 | ||
ST-elevation myocardial infarction | 3.13 (1.12–8.71) | 0.029 | 1.97 (0.57–6.77) | 0.284 |
Non ST-elevation myocardial infarction | 0.39 (0.12–1.23) | 0.108 |
OR odds ratio, CI confidence interval, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, TIA transient ischemic attack, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker