Table 7.
Analysis | ||||
---|---|---|---|---|
Single | Multiple | |||
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age (years) | 4.19 (0.50–35.1 | 0.187 | ||
Male | 0.26 (0.08–0.85) | 0.025 | 0.33 (0.06–1.69) | 0.182 |
Body mass index | 2.13 (0.61–7.43) | 0.234 | ||
Diabetes mellitus | 1.52 (0.47–4.88) | 0.482 | ||
Hypertension | 1.23 (0.38–4.05) | 0.728 | ||
Dyslipidemia | 0.67 (0.18–2.52) | 0.547 | ||
Chronic kidney disease | 0.66 (0.16–2.66) | 0.558 | ||
Current smoker | 0.38 (0.10–1.51) | 0.170 | ||
Obstructive sleep apnea | 5.46 (1.69–17.6) | 0.005 | ||
Apnea hypopnea index | 8.04 (2.36–27.3) | 0.001 | 9.44 (1.99–44.9) | 0.005 |
Family history of coronary artery disease | 2.41 (0.59–9.84) | 0.220 | ||
History of PCI or CABG | 0.99 (0.33–2.99) | 0.981 | ||
History of myocardial infarction | 0.50 (0.13–1.97) | 0.318 | ||
Prior statin use | 1.48 (0.48–4.57) | 0.493 | ||
Prior aspirin use | 0.53 (0.17–1.63) | 0.525 | ||
Prior clopidogrel use | 0.28 (0.06–1.38) | 0.118 | ||
Prior ACEI or ARB | 1.06 (0.32–3.51) | 0.930 | ||
Prior calcium channel blocker use | 0.42 (0.11–1.64) | 0.211 | ||
Prior beta blocker use | 0.38 (0.10–1.51) | 0.170 | ||
Prior eicosapentaenoic acid | 1.28 (0.23–7.29) | 0.781 | ||
Prior ezetimibe | 0.77 (0.08–7.36) | 0.817 | ||
Hemoglobin (g/dl) | 0.12 (0.04–0.42) | 0.001 | 0.18 (0.04–0.79) | 0.022 |
HbA1c (%) | 1.86 (0.62–5.59) | 0.271 | ||
Glucose (mg/dl) | 6.32 (0.77–51.9) | 0.086 | ||
LDL-C (mg/dl) | 1.88 (0.62–5.73) | 0.266 | ||
Triglyceride (mg/dl) | 0.58 (0.19–1.75) | 0.334 | ||
HDL-C (mg/dl) | 6.72 (1.77–25.5) | 0.005 | 5.31 (1.03–27.3) | 0.046 |
LDL-C to HDL-C ratio | 0.33 (0.09–1.13) | 0.078 | ||
Acute coronary syndrome | 0.68 (0.23–2.05) | 0.496 | ||
ST-elevation myocardial infarction | 0.33 (0.08–1.28) | 0.108 | ||
Non ST-elevation myocardial infarction | 1.86 (0.57–6.09) | 0.303 |
OR odds ratio, CI confidence interval, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, TIA transient ischemic attack, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker