Table 2.

Specific inclusion and exclusion criteria for queries of the Danish registries

Phenotype	ICD-10 inclusion criteria	Age-specific inclusion criteria	Exclusion criteria
ASD	F84.0	Diagnosis made at age 1 or later	None
SCZ	F20	Diagnosis made at age 10 or later	None
ID	F70-F79	Diagnosis made at age 1 or later	None
EP	G40.4C, G40.4E OR one of G40 with no additional specifications, G40.3 (any additional specification except G40.3F), G40.4 (any additional specification), G40.8, G40.9 with no additional specifications AND one of F70-F73, F78, F79, F84 with no additional specifications, F84.0, F84.8, F84.9	Epilepsy diagnosis made by age 18	Anyone with unknown parent, anyone with a parent who has any ICD-10 or ICD-8 epilepsy diagnosis, anyone with ICD-10 P code, or any of the following diagnostic codes recorded earlier than 1 year following the epilepsy diagnosis: A17, A39, A80-A89, C70, C71, E70-72, E74-80, E83, E85, E88, G00-G09
CHD	All ICD codes listed in Table 3, except Q21.1	Diagnosis made within 1 year of birth	one

For each disorder, we describe the ICD-10 codes used to query the Danish data for comparable cases, as well as any age of diagnosis restrictions we applied to the data. We also describe the exclusion criteria applied to epilepsy cases