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. 2019 Jul 9;6(4):ENEURO.0160-19.2019. doi: 10.1523/ENEURO.0160-19.2019

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Copyright © 2019 Matikainen-Ankney et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Ad libitum HFD decreases mouse home cage activity over time. A, Time course of mouse weight over time. B, Point plot showing average weights at weeks 0 and 9; HFD group had significant increase in weight compared to chow; p = 3.475723e-09, F = 60.093562. C, Time course showing, over nine weeks, mice fed HFD exhibited decreasing activity over time relative to chow controls. D, Point plot showing average activity levels normalized to baseline between chow and HFD groups; HFD group had significantly decreased average activity levels compared to chow; p = 0.000997, F = 13.300153. In B, D, two-way ANOVAs performed, stats reported for significant interactions between group and time; n = 10 mice per group.