Table 2. AD biomarker levels in the cerebrospinal fluid.
| iNPH | AD | CN | p1 | p2 | p3 | |
|---|---|---|---|---|---|---|
| Aβ42 (pg/mL) | 892.8±311.4 | 391.8±120.2 | 1330.0±99.7 | <0.001 | 0.089 | <0.001 |
| Aβ40 (pg/mL) | 5504.0±2867.1 | 5462.5±2192.2 | 9179.6±2596.9 | 1.000 | 0.082 | 0.032 |
| Aβ42/Aβ40 ratio | 0.187±0.068 | 0.077±0.020 | 0.155±0.044 | 0.001 | 0.178 | 0.003 |
| t-tau (pg/mL) | 238.9±103.7 | 720.7±220.1 | 294.5±95.1 | <0.001 | 1.000 | <0.001 |
| p-tau (pg/mL) | 30.4±9.5 | 78.1±30.6 | 36.2±11.1 | 0.001 | 0.560 | <0.001 |
Data are mean±standard-deviation values.
Aβ: β-amyloid, AD: Alzheimer's disease, CN: cognitively normal, iNPH: idiopathic normal-pressure hydrocephalus, t-tau: total tau, p1: iNPH vs. AD, p2: iNPH vs. CN, p3: AD vs. CN, p-tau: phosphorylated tau.