Table 1. Baseline characteristics of subjects according to the nutritional status.
| Well nourished (n=143, 67.4%) | At-risk/malnutrition (n=69, 32.6%) | Total (n=212) | p | |
|---|---|---|---|---|
| Age, years | 68.4±7.8 | 72.8±8.4 | 69.8±8.2 | <0.001 |
| Sex, male | 75 (52.4) | 21 (30.4) | 96 (45.3) | 0.004 |
| Education, years | 10.0±5.0 | 8.5±4.8 | 9.5±5.0 | 0.041 |
| Caregiver | 125 (87.4) | 64 (92.8) | 189 (89.2) | 0.349 |
| Hypertension | 62 (43.4) | 32 (47.1) | 94 (44.5) | 0.566 |
| DM | 20 (14.0) | 14 (20.6) | 34 (16.1) | 0.308 |
| Diagnosis | <0.001 | |||
| CU | 93 (65.0) | 26 (37.7) | 119 (56.1) | |
| MCI | 42 (29.4) | 14 (20.3) | 56 (26.4) | |
| Dementia | 8 (5.6) | 29 (42.0) | 37 (17.5) | |
| MMSE score | 25.1±3.9 | 21.3±6.1 | 23.9±5.1 | <0.001 |
| CDR-SOB score | 0.5±1.1 | 2.3±2.7 | 1.1±2.0 | <0.001 |
| GDpS score | 8.2±6.2 | 13.0±7.4 | 9.7±7.0 | <0.001 |
| SNAQ score | 14.8±2.0 | 13.4±2.3 | 14.4±2.2 | <0.001 |
| BMI | 24.5±3.6 | 22.5±2.7 | 23.9±3.4 | <0.001 |
| Albumin | 4.4±0.3 | 4.4±0.4 | 4.4±0.3 | 0.883 |
| Total cholesterol | 179.4±37.3 | 181.9±34.5 | 180.2±36.3 | 0.634 |
| HDL-C | 50.8±13.3 | 52.6±12.8 | 51.4±13.1 | 0.341 |
| LDL-C | 103.4±30.4 | 106.4±30.5 | 104.4±30.4 | 0.509 |
| Triglycerides | 155.3±91.2 | 142.7±78.9 | 151.2±87.4 | 0.325 |
| Hemoglobin | 13.8±1.3 | 12.8±1.2 | 13.5±1.3 | <0.001 |
| ApoE ε4 | 0.385 | |||
| 0 copies | 109 (76.2) | 48 (69.6) | 157 (74.1) | |
| 1+ copies | 34 (23.8) | 21 (30.4) | 55 (25.9) | |
| Amyloid positivity, n (%) | 25 (17.5) | 37 (54.5) | 62 (29.4) | <0.001 |
Data are mean±SD values except where indicated otherwise. Independent t-tests and chi-square tests were used to examine between-group differences in continuous variables and categorical variables, respectively.
BMI: body mass index, CDR-SOB: Clinical Rating Scale Sum of Boxes, CU: cognitively unimpaired, DM: diabetes mellitus, GDpS: Geriatric Depression Scale, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, MCI: mild cognitive impairment, MMSE: Mini Mental State Examination, SNAQ: Simplified Nutritional Appetite Questionnaire.