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. 2019 Jul 10;9:9982. doi: 10.1038/s41598-019-46374-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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FICZ photostability (a) FICZ (1) and ICZ (12) decompose to quinone (13) (b) Time course of FICZ (1) ● and ICZ (12) О stability in air and bright light (c) Time course of FICZ (1) stability in air and bright light ● or direct sunlight ▲ (d) FICZ (1) stability in (A) air and light ●, (B) nitrogen and light О, (C) air and dark ▲, and (D) nitrogen and dark △ (e) Representative data from a duplicate experiment measuring activation of the human AhR in a cyp1a1 reporter gene assay by a freshly prepared sample of FICZ (1), ICZ (12), or quinone (13).