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. 2019 Jul 3;10:737. doi: 10.3389/fphar.2019.00737

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Copyright © 2019 Ma, Liu, Liu, Wang, Chang, Li, Li, Hou and Bai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PEI and CBPP increased phosphorylation of MLC2 and improved lung function. (A) HBSMC cells were stimulated by 10 µM PEI, phosphorylation of MLC2 was measured by Western blot, and the relative intensity data of P-MLC2^S19 to GAPDH are represented by the mean ± SD of three groups, **p < 0.01 and ***p < 0.001. (B) HE staining images (400-fold) of bronchus, the statistics of bronchial wall thickness (C), exfoliation of lung epithelial cells (D), and MLI (E) in bronchus pathological section. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to the Mod. ^## p < 0.01 and ^### p < 0.001, compared to the Con (n = 6).