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Production of CXCL2, CCL8, and IL-1β by gingival tissue from normal and diabetic mice 14 days after PD. (A) CXCL2, (B) CCL8, and (C) IL1β by ELISA. Data represented as mean ± SEM (n = 10). Statistical differences represented by *p < 0.05, **p < 0.01, and ****p < 0.0001 (Control vs. PD; PD vs. Alisk + PD; and PD vs. PD+Alisk).
