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. 2019 Jul 4;11:172. doi: 10.3389/fnagi.2019.00172

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Copyright © 2019 Nizari, Carare, Romero and Hawkes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regional comparison of measures of the NVU. (A,B) Total density of ChAT-positive fibers in the cortex and hippocampus in control mice (A) and following administration of saporin (B). (C–H) Quantification of area of contact between ChAT-positive fibers and collagen IV (C,D), SMA (E,F) and astrocyte endfeet (G,H) in the cortex and hippocampus in control (C,E,G) and saporin-treated mice (D,F,H). Data represent mean ± SEM. *p < 0.05, paired two-tailed Student’s t-test (A,B), Kruskal-Wallis with Dunn’s post hoc test, (C,D), Wilcoxon matched paired test (E–H).