Table 3.
Astrocyte endfoot coverage of basement membrane. Area of contact/length (μm2/μm) ± SEM | Hippocampus | Cortex | Striatum | ||||||
---|---|---|---|---|---|---|---|---|---|
Capillaries | Arteries | Veins | Capillaries | Arteries | Veins | Capillaries | Arteries | Veins | |
Control | 6.7 ± 2.1* | 38.43 ± 8.8▴ | 81.84 ± 21.4*▴ | 2.23 ± 1.5 | 23.72 ± 13.8 | 10.24 ± 6.1▴ | 0.32 ± 0.2 | 0.357 ± 0.08▴ | 0.457 ± 0.2▴ |
Saporin | 15.26 ± 3.5* | 52.54 ± 12▴ | 84.35 ± 14.4*▴ | 4.22 ± 1.8 | 21.05 ± 6.6 | 8.57 ± 5.3▴ | 0.317 ± 0.2 | 0.105 ± 0.03▴ | 0.121 ± 0.06▴ |
Values represent mean ± SEM. *p < 0.05 capillaries vs. veins (two-way repeated measures ANOVA with Sidak’s post hoc) ▴p < 0.05; hippocampus vs. cortex or striatum (two-way repeated measures ANOVA with Sidak’s post hoc).