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A–C: urinary excretion rates of 2′,3′-cAMP, 2′-AMP, and 3′-AMP in 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) wild-type (CNPase+/+) and knockout (CNPase−/−) mice. D: urinary 2′-AMP-to-3′-AMP ratio in CNPase+/+ and CNPase−/− mice. Values are means ± SE.
