Table 1.

Echocardiogram data for female SS and SS-3^BN rats treated with 24 Gy of localized, image-guided irradiation

	Baseline		3 mo		5 mo
	SS	SS-3BN	SS	SS-3BN	SS	SS-3BN
IVSd, cm/kg	0.83 ± 0.03	0.91 ± 0.03	1.08 ± 0.05	0.99 ± 0.06	0.90 ± 0.04	0.96 ± 0.06
LVIDd, cm/kg	3.01 ± 0.16	3.23 ± 0.08	2.42 ± 0.09	2.47 ± 0.14	2.68 ± 0.11	2.61 ± 0.06
LVIDs, cm/kg	1.44 ± 0.18	1.44 ± 0.09	1.08 ± 0.15	0.75 ± 0.07	1.33 ± 0.14	0.99 ± 0.06*
LVPWd, cm/kg	0.92 ± 0.06	0.86 ± 0.02	1.03 ± 0.05	0.89 ± 0.03*	0.94 ± 0.03	0.96 ± 0.07
EDV, ml/kg	2.72 ± 0.40	2.79 ± 0.17	2.01 ± 0.17	1.97 ± 0.26	2.58 ± 0.18	2.15 ± 0.12
ESV, ml/kg	0.35 ± 0.13	0.29 ± 0.05	0.29 ± 0.11	0.07 ± 0.01	0.49 ± 0.10	0.14 ± 0.02†
SV, ml/kg	2.36 ± 0.31	2.49 ± 0.13	1.72 ± 0.11	1.89 ± 0.25	2.08 ± 0.19	2.01 ± 0.11
LVM, g/kg	5.71 ± 0.16	5.87 ± 0.10	6.32 ± 0.20	5.56 ± 0.13*	6.04 ± 0.23	5.92 ± 0.30
FS, %	53.36 ± 3.82	55.54 ± 1.97	56.18 ± 5.15	69.35 ± 2.06	45.87 ± 4.41	62.34 ± 1.97†
EF, %	87.96 ± 3.09	89.89 ± 1.25	87.59 ± 4.03	96.44 ± 0.56	80.93 ± 3.88	93.64 ± 0.84†

Values are means ± SE. EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; FS, fractional shortening; IVSd, interventricular septal wall thickness during diastole; LVIDd, left ventricular internal diameter at end diastole; LVIDs, left ventricular internal diameter at end systole; LVM, left ventricular mass; LVPWd, left ventricular posterior wall thickness at diastole; SS, Dahl salt-sensitive/Mcwi; SS-3^BN, substitution of rat chromosome 3 from the resistant Brown Norway rat strain onto the SS background; SV, stroke volume.

^*P < 0.05;

^†P < 0.01.