Fig. 7.

Synergistic effect of kinase inhibitors KN93 and H89 with respect to right ventricle (RV) conduction slowing. Values on the graph represent group-wise means ± SE of the average RV and left ventricle (LV) local conduction delays after 15 min of drug perfusion. All data obtained during pacing at cycle length (CL) = 400 ms from an LV location. Two-way ANOVA with the Tukey-Kramer post-hoc test was performed to assess how chamber and drug combination affected the mean conduction delays. #P < 0.05 vs. RV in the same experimental group; brackets indicate P < 0.05 vs. drug combination.