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. 2019 Jul 5;12:5335–5354. doi: 10.2147/OTT.S198750

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© 2019 Shi et al.

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siRNA-mediated downregulation of GATA1 impedes tumor initiation and tumor growth in vivo. (A) Tumor growth curve of the xenograft tumor of nude mice injected with GATA1, si-GATA1, LY294002 and si-GATA1+LY294002; (B) representative images of tumors of nude mice injected with GATA1, si-GATA1, LY294002 and si-GATA1+LY294002 at 28th day. *p<0.05 vs the blank and NC groups; #p<0.05 vs the si-GATA1 and LY294002 groups. Measurement data were expressed as means±standard deviation. The count data were expressed as a percentage or a ratio. Comparison between multiple groups at different time points using repeated measures ANOVA.