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. 2019 Jul 5;12:5335–5354. doi: 10.2147/OTT.S198750

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© 2019 Shi et al.

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siRNA-mediated downregulation of GATA1 represses the self-renewal ability of CCA stem cells. (A) The number and volume of spheres after transfection with GATA1, si-GATA1, LY294002 and si-GATA1+LY294002 assessed by spheroid formation assay. (B) Statistics regarding the number and volume of spheres after transfection with GATA1, si-GATA1, LY294002 and si-GATA1+LY294002. *p<0.05 vs the blank and NC groups; #p<0.05 vs the si-GATA1 and LY294002 groups.