Table 2.
Retrieval of CCA-related genes (Top 10)
| Gene | Gene name | Score | PMIDs |
|---|---|---|---|
| TP53 | Tumor protein p53 | 0.291 | 24 |
| PTGS2 | Prostaglandin-endoperoxide synthase 2 | 0.215 | 19 |
| EGFR | Epidermal growth factor receptor | 0.213 | 21 |
| ERBB2 | Erb-b2 receptor tyrosine kinase 2 | 0.211 | 14 |
| IL6 | Interleukin 6 | 0.208 | 18 |
| KRAS | KRAS proto-oncogene, GTPase | 0.205 | 13 |
| SLC5A5 | Solute carrier family 5 member 5 | 0.203 | 1 |
| GNAS | GNAS complex locus | 0.203 | 2 |
| PTEN | Phosphatase and tensin homolog | 0.201 | 6 |
| IDH2 | Isocitrate dehydrogenase (NADP (+)) 2, mitochondria | 0.201 | 5 |
Notes: Score of the reliability of the gene-disease pair, based on the type and number of sources where is reported, and the number of PMIDs; PMIDs: Total number of PMIDs supporting the association.
Abbreviation: CCA, cholangiocarcinoma.