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The proportion of CCA stem cells treated with GATA1, si-GATA1, LY294002 and si-GATA1+LY294002 in vivo
| Injected cells | Blank | NC | GATA1 | si-GATA1 | LY294002 | si-GATA1+LY294002 |
|---|---|---|---|---|---|---|
| 1,000,000 | 5/6 | 5/6 | 6/6 | 4/6 | 4/6 | 3/6 |
| 100,000 | 4/6 | 3/6 | 5/6 | 3/6 | 2/6 | 2/6 |
| 10,000 | 3/6 | 2/6 | 5/6 | 2/6 | 2/6 | 2/6 |
| 1,000 | 0/6 | 1/6 | 4/6 | 1/6 | 0/6 | 1/6 |
| Total | 12/24 | 11/24 | 20/24 | 10/24 | 8/24 | 8/24 |
Abbreviations: CCA, cholangiocarcinoma; GATA1, GATA binding protein-1; si, small interfering; NC, negative control.
