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. 2019 Mar 24;7(6):825–837. doi: 10.1177/2050640619840147

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Figure 1. — Temporal relationship between courses of intravenous MP pulse and liver biochemistry in four patients. The data shown correspond to patient 1 with a single episode after exposure to MP (a), patient 2 who developed after a first episode up to three more events of MP hepatotoxicity (b) and patient 3 who after a first event of MP-induced liver injury suffered from rechallenge due to MP (c).Concomitant treatments present at onset of each liver dysfunction episode are displayed. Abbreviations: MP: methylprednisolone; TBL: serum total bilirubin (mg/dl); ALT: alanine aminotransferase (U/L); ALP: alkaline phosphatase (U/L); interferon-β: interferon beta; Bx: biopsy; g: gram; d: day; i.v.: intravenous; RC: rechallenge; CaC: calcium carbonate; CaG: calcium gluconate; MCP: metoclopramide; prn: pro re nata.