Table 1.

Study schedule of events.

Procedures		Screening	Postentry evaluations (months)a
			0	1	2	3	4	5	6	7	8	9	10	11	12
Informed consent		Xb	X	—c	—	—	—	—	—	—	—	—	—	—	—
Medical history		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Medication history		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Clinical assessment		X	—	X	—	X	—	—	X	—	—	X	—	—	X
Complete physical exam		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Targeted physical exam			—	X	—	X	—	—	X	—	—	X	—	—	X
Computer-assisted self-interview		X	—	—	—	X	—	—	X		—	X	—	—	X
Complete blood count		X	—	X	—	X	—	—	X	—	—	—	—	—	X
Liver and renal function tests		X	—	X	—	X	—	—	X	—	—	—	—	—	X
Fasting glucose and lipids			X	—	—	—	—	—	X	—	—	—	—	—	X
Estradiol and total testosterone			X	—	—	X	—	—	X	—	—	—	—	—	X
Chest x ray and sputum samples		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Risk reduction counseling, condoms, and lubricants		X	X	—	—	X	—	—	X	—	—	X	—	—	X
Sampling for Neisseria gonorrhoeae and Chlamydia trachomatis testing		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Sampling for anal cytological abnormalities		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Syphilis serology		X	—	—	—	X	—	—	X	—	—	X	—	—	X
Hepatitis B and hepatitis C serology		X	—	—	—	—	—	—	—	—	—	—	—	—	—
HIV serology		X	—	—	—	—	—	—	—	—	—	—	—	—	—
Care of HIV negative			—	—	—	—	—	—	—	—	—	—	—	—	—
	HIV serology		—	—	—	X	—	—	X	—	—	X	—	—	X
	Pre-exposure prophylaxis dispensation		X	X	—	X	—	—	X	—	—	X	—	—	X
Care of HIV positive			—	—	—	—	—	—	—	—	—	—	—	—	—
	CD4+ cell count		X	—	—	—	—	—	X	—	—	—	—	—	X
	HIV-1 RNA		X	—	—	X	—	—	X	—	—	—	—	—	X
	Antiretroviral treatment dispensation		X	X	—	X	—	—	X	—	—	X	—	—	X
Feminizing hormone therapy			—	—	—	—	—	—	—	—	—	—	—	—	—
	Adherence counseling and education		X	X	—	X	—	—	X	—	—	X	—	—	X
	Dispensation		X	X	X	X	X	X	X	X	X	X	X	X	X
Peer health navigation support		X	X	X	X	X	X	X	X	X	X	X	X	X	X

^aVisits to occur every 30 days ± 5 days.

^bThe procedure is indicated at the specific study visit.

^cNot applicable.