Table 3.
Summary of the relative optical densities of COMT and D1R in the dorsal and ventral striatum
| Marker | Area | wt, SAL | wt, POL | Nurr1+/−, SAL | Nurr1+/−, POL |
|---|---|---|---|---|---|
| COMT | CPu | 2.46 ± 0.36 | 2.35 ± 0.27 | 2.32 ± 0.18 | 2.41 ± 0.32 |
| NAc core | 2.29 ± 0.21 | 2.07 ± 0.27 | 2.11 ± 0.16 | 2.23 ± 0.26 | |
| NAc shell | 2.06 ± 0.20 | 1.98 ± 0.31 | 2.01 ± 0.21 | 2.10 ± 0.34 | |
| D1R | CPu | 3.86 ± 0.10 | 3.79 ± 0.15 | 3.82 ± 0.18 | 3.78 ± 0.22 |
| NAc core | 3.34 ± 0.14 | 3.28 ± 0.23 | 3.31 ± 0.11 | 3.36 ± 0.20 | |
| NAc shell | 3.08 ± 0.17 | 2.97 ± 0.20 | 3.01 ± 0.18 | 3.10 ± 0.33 |
The table summarizes the ln-transformed measures obtained in the CPu, NAc core, and NAc shell subregions of the striatum for wt and Nurr1+/− offspring subjected to prenatal saline (SAL) or poly(I:C) (POL) treatment. All values are means ± SEM; N = 7 in each experimental group and for each measure.