Table 3.
Cluster level |
Voxel level |
Coordinates of peak voxel |
Cluster comprising | ||||
---|---|---|---|---|---|---|---|
pcorr | kE | T | puncorr | x | y | z | |
ANX > CTRL | |||||||
0.001 | 2270 | 6.10 | <0.001 | 0.0 | 0.2 | −7.4 | Bed nucleus of the stria terminalis (mainly medial and lateral division), nucleus accumbens (core and shell), medial and lateral septal nucleus, and medial and lateral preoptic area |
ANX < CTRL | |||||||
<0.001 | 3055 | 8.97 | <0.001 | −5.0 | −3.4 | −4.0 | L primary somatosensory cortex (barrel field, upper lip, forelimb and hindlimb, shoulder and trunk regions) and L hippocampus (field CA1 and CA2) |
<0.001 | 4382 | 7.86 | <0.001 | 5.0 | −3.4 | −4.2 | R primary somatosensory cortex (barrel field, upper lip, forelimb and hindlimb, shoulder and trunk regions) |
ANX > FEAR | |||||||
0.301 | 577 | 4.75 | <0.001 | −2.0 | −1.0 | −8.6 | Bed nucleus of the stria terminalis (mainly medial and lateral division), nucleus accumbens (core and shell), medial and lateral septal nucleus, and medial and lateral preoptic area |
ANX < FEAR | |||||||
0.659 | 338 | 4.22 | 0.001 | 3.6 | −0.8 | −2.6 | R primary somatosensory cortex (mainly forelimb, shoulder, and trunk regions) |
Negative correlation with freezing during acclimation on posttest in the ANX subgroup | |||||||
<0.001 | 211 | 35.87 | <0.001 | 5.8 | 0.6 | −3.4 | R primary somatosensory cortex (mainly upper lip region) |
Positive correlation with exploring during acclimation on posttest in the ANX subgroup | |||||||
<0.001 | 265 | 34.09 | <0.001 | −6.0 | −1.4 | −3.6 | L primary somatosensory cortex (mainly barrel field, upper lip, and forelimb regions) |
The x-coordinate corresponds to the distance (in millimeters) lateral to midline (right is positive), the y-coordinate indicates the position relative to bregma (anterior is positive), and the z-coordinate denotes the dorsoventral position. pcorr, cluster-corrected p value; kE, cluster extent (voxels); T, peak voxel t statistic; puncorr, uncorrected height p value. All (de)activated brain regions are bilateral, unless stated otherwise (L, left; R, right).