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A schematic summary of the dFMRP interactions and regulation in Drosophila neurons described herein. The adenylyl cyclase (AC) at the cell membrane (top curved line) is hypothesized to be Rutabaga, based on the results of Bolduc et al. (2008). DmGluRA is shown to inhibit its activity, while itself is negatively regulated by dFMRP. Positive transcriptional regulation of dfmr1 by cAMP levels via protein kinase A is also indicated. The cell nucleus is indicated by the dotted line.
