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. 2019 Jul 4;7:475. doi: 10.3389/fchem.2019.00475

Table 2.

Minimum Inhibitory Concentration (MIC, μM) of TMP and the new GBBR analogs in combination with Sulfamethoxazole (1:20) against E. coli ATCC 25922, S. aureus ATCC 29213, P. aeruginosa PAO1, S. aureus 8125304770, S. aureus 8139265926, S. aureus 8125255044, and S. aureus 8124825998.

MIC (μM)
E. coli ATCC 25922 S. aureus ATCC 29213 P. aeruginosa PAO1 S. aureus 8125304770 S. aureus 8139265926 S. aureus 8125255044 S. aureus 8124825998
TMP 1 0.11 0.43 13.78 0.431 0.86 0.22 0.43
4a 2.02 8.06 > 64.52 4.03 8.06 1.01 4.03
4b 67.01 > 67.01 > 67.01 67.01 > 67.01 67.01 > 67.00
4c 1.17 4.68 37.42 4.68 9.36 0.292 1.17
4d 2.05 4.09 > 65.50 4.09 4.093 1.02 4.09
4e 1.30 5.19 > 83.07 1.298 2.60 0.65 1.30
4f 0.63 5.01 40.05 0.63 2.50 0.63 1.25
4g 0.54 4.32 > 69.18 2.16 8.65 1.08 4.32
4h 0.27 2.14 34.22 1.07 1.07 0.27 1.07
4i 0.13 2.05 32.75 0.51 1.02 0.51 1.02
4j 0.26 2.05 32.75 1.02 2.05 0.51 1.02
5a > 45.60 > 45.60 > 45.60 > 45.60 > 45.60 > 45.60 > 45.60
5b 28.33 > 56.66 > 56.66 28.331 > 56.66 14.17 56.66
6a 2.27 9.09 > 72.75 2.27 4.55 1.14 4.55
6b 0.31 2.46 78.73 1.23 2.46 0.62 2.46
7a > 54.29 > 54.29 > 54.29 > 54.9 > 54.29 > 54.29 > 54.29