Behavioral effects of ketamine administration. A, Effect of ketamine on the directional error rates (blue bars), response rates (green bars), and fixation error rates (red bars). The darker shaded foreground bars represent preinjection values, and the lighter background bars are postinjection values. Data for monkey O were averaged from 8 experiment sessions; data for monkey W were averaged from 10 experiment sessions. B, Effect of ketamine on saccade reaction times. The format is the same as in A, with blue bars representing saccade reaction times on correct trials and red bars representing saccade reaction times on (directional) error trials. Error bars indicate SEM. *p < 0.05, **p < 0.01, ***p < 0.001.